Preservative solution for freeze-storage of surgically excised human colon to enable study of smooth muscle function in vitro

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Preservative solution for freeze-storage of surgically excised human colon to enable study of smooth muscle function in vitro.

We have compared the reactivity to carbachol and high potassium of circular smooth muscle isolated from segments of human colon which was freeze-stored in different preservative solutions for more than one month following surgical resection. Concentration-dependent contractions in response to carbachol were reduced in terms of both their sensitivity (pEC50) and reactivity (Emax), depending on t...

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ژورنال

عنوان ژورنال: Journal of Smooth Muscle Research

سال: 2004

ISSN: 0916-8737,1884-8796

DOI: 10.1540/jsmr.40.177